报错 求帮助

org.mybatis.spring.MyBatisSystemException: nested exception is org.apache.ibatis.exceptions.PersistenceException: 

### Error querying database.  Cause: org.springframework.jdbc.CannotGetJdbcConnectionException: Could not get JDBC Connection; nested exception is java.sql.SQLException: An attempt by a client to checkout a Connection has timed out.

### The error may exist in file [E:\seckill2\target\classes\mapper\SeckillDao.xml]

### The error may involve org.seckill.dao.SeckillDao.queryAll

### The error occurred while executing a query

### Cause: org.springframework.jdbc.CannotGetJdbcConnectionException: Could not get JDBC Connection; nested exception is java.sql.SQLException: An attempt by a client to checkout a Connection has timed out.

这个是报错信息 早上运行都还是可以的 晚上运行就不行了  求大神指教